MIA3

Across TCGA patient cohorts, MIA3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,567 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MIA3-associated genes across cancer lineages are NES, ARHGAP10, and XBP1. Each is linked with MIA3 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIA3-to-partner and partner-to-MIA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIA3 versus NES in BRCA, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIA3→partner) and Y-score (partner→MIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NES →	-0.833	-0.365	<.001	<.001	3	5
UCEC	ARHGAP10 →	-0.717	-0.497	<.001	<.001	3	5
BRCA	XBP1 →	+1.378	+0.447	.001	<.001	3	5
BRCA	LINC02489 →	+1.533	+0.559	<.001	<.001	3	5
UCEC	FBXO17 →	-0.850	-0.367	<.001	<.001	3	5
BRCA	ST8SIA1 →	-0.679	-0.433	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,567 associations by consensus.

MIA3 vs NES — BRCA

Explore this scatter interactively →