MIA3

Across TCGA cell cohorts, MIA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,499 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MIA3-associated GO terms across cancer lineages are Establishment of protein localization to endoplasmic reticulum membrane, Golgi vesicle transport, and Viral translational termination-reinitiation. Each is linked with MIA3 in more than 15 cancer types. Because this analysis shows association rather than direction, both MIA3-to-partner and partner-to-MIA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to endoplasmic reticulum membrane grouped by MIA3-low versus MIA3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIA3→partner) and Y-score (partner→MIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of protein localization to endoplasmic reticulum membrane →	+0.122	+0.539	<.001	.004	2	16
OESOPHAGUS	Golgi vesicle transport →	+0.064	+0.520	.002	.002	2	14
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.087	+0.639	<.001	.001	3	12
SKIN	COPII-coated vesicle cargo loading →	+0.118	+0.597	<.001	<.001	3	12
OESOPHAGUS	Cytosolic transport →	+0.061	+0.609	<.001	<.001	3	12
OESOPHAGUS	Regulation of myoblast fusion →	+0.117	+0.608	.004	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,499 associations by consensus.

Establishment of protein localization to endoplasmic reticulum membrane by MIA3 expression — LUNG_SCLC

Explore this box plot interactively →