MGAT5B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MGAT5B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,127 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MGAT5B-associated GO terms across cancer lineages are Positive regulation of cell-substrate junction organization, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with MGAT5B in more than 10 cancer types. Because this analysis shows association rather than direction, both MGAT5B-to-partner and partner-to-MGAT5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell-substrate junction organization grouped by MGAT5B-low versus MGAT5B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT5B→partner) and Y-score (partner→MGAT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEPositive regulation of cell-substrate junction organization →+0.145+2.015.002<.001311
STOMACHResponse to oscillatory fluid shear stress →+0.239+1.860<.001<.001311
STOMACHCellular response to oscillatory fluid shear stress →+0.239+1.860<.001<.001311
STOMACHVascular endothelial cell response to oscillatory fluid shear stress →+0.239+1.860<.001<.001311
LUNG_NSCLC_LUSCProtein depolymerization →+0.116+1.985.002.005311
BREASTProtein-containing complex disassembly →+0.050+1.147<.001.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,127 associations by consensus.

Positive regulation of cell-substrate junction organization by MGAT5B expression — BONE

Box plot of Positive regulation of cell-substrate junction organization in MGAT5B-low vs MGAT5B-high samples in BONE.

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Exploration