MGAT5B

Across TCGA cell cohorts, MGAT5B mutation is significantly associated with the RNA expression of many other genes, with 150 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MGAT5B-associated genes across cancer lineages are MROH2B, MAPKAPK5, and HTR3C. Each is linked with MGAT5B in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAT5B-to-partner and partner-to-MGAT5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MROH2B grouped by MGAT5B-low versus MGAT5B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT5B→partner) and Y-score (partner→MGAT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MROH2B →	+0.063	+4.643	<.001	.005	3	2
LARGE_INTESTINE	MAPKAPK5 →	+0.426	+3.299	.008	.004	3	2
SOFT_TISSUE	HTR3C →	+0.064	+4.169	<.001	.002	3	1
SOFT_TISSUE	TRIM40 →	+0.008	+3.882	.009	.004	3	1
SOFT_TISSUE	OR6C3 →	+0.443	+4.392	<.001	.004	3	1
SOFT_TISSUE	OR6C1 →	+0.860	+4.392	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 150 associations by consensus.

MROH2B by MGAT5B expression — BLOOD_Lymphoma

Explore this box plot interactively →