MGAT4C

Across TCGA cell cohorts, MGAT4C mutation is significantly associated with the RNA expression of many other genes, with 167 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MGAT4C-associated genes across cancer lineages are SPACA1, ACSM2A, and SLC36A3. Each is linked with MGAT4C in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAT4C-to-partner and partner-to-MGAT4C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPACA1 grouped by MGAT4C-low versus MGAT4C-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAT4C→partner) and Y-score (partner→MGAT4C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SPACA1 →	+0.023	+5.285	<.001	.003	3	1
LUNG_SCLC	ACSM2A →	+0.028	+4.523	<.001	.003	3	1
LUNG_SCLC	SLC36A3 →	+0.022	+5.169	<.001	<.001	3	1
LUNG_SCLC	OR11G2 →	+0.022	+4.643	<.001	.004	3	1
LUNG_SCLC	PRR20B →	+0.022	+4.269	.001	.005	3	1
LUNG_SCLC	PRR20A →	+0.022	+4.269	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 167 associations by consensus.

SPACA1 by MGAT4C expression — STOMACH

Explore this box plot interactively →