MGAM2

Across TCGA patient cohorts, MGAM2 protein abundance is significantly associated with the RNA expression of many other genes, with 687 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MGAM2-associated genes across cancer lineages are OR7E87P, SPECC1L, and YPEL1. Each is linked with MGAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MGAM2-to-partner and partner-to-MGAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MGAM2 versus OR7E87P in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAM2→partner) and Y-score (partner→MGAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR7E87P →	+0.222	+1.486	.005	.004	3	2
PDAC	SPECC1L →	-0.268	-0.970	.002	.001	3	1
PDAC	YPEL1 →	-0.343	-0.892	.003	.003	3	1
PDAC	HPS4 →	-0.278	-0.764	.001	<.001	3	1
PDAC	TFIP11 →	-0.261	-0.830	<.001	<.001	3	1
PDAC	MICALL1 →	-0.498	-1.091	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 687 associations by consensus.

MGAM2 vs OR7E87P — BRCA

Explore this scatter interactively →