MGAM

Across TCGA cell cohorts, MGAM RNA expression is significantly associated with the go_rna of many other GO terms, with 1,742 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MGAM-associated GO terms across cancer lineages are Disaccharide catabolic process, Protein localization to vacuole, and Vacuolar transport. Each is linked with MGAM in more than 14 cancer types. Because this analysis shows association rather than direction, both MGAM-to-partner and partner-to-MGAM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Disaccharide catabolic process grouped by MGAM-low versus MGAM-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MGAM→partner) and Y-score (partner→MGAM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Disaccharide catabolic process →	+1.291	+2.224	.001	<.001	3	15
BLOOD_Lymphoma	Protein localization to vacuole →	+0.045	+0.090	<.001	.003	3	9
BLOOD_Leukemia	Vacuolar transport →	+0.030	+0.730	<.001	.009	3	8
SKIN	Endosomal transport →	+0.052	+1.774	.001	.001	3	8
SKIN	Protein targeting to ER →	+0.091	+1.688	.001	.002	3	7
KIDNEY	Establishment of protein localization to endoplasmic reticulum →	+0.087	+0.252	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,742 associations by consensus.

Disaccharide catabolic process by MGAM expression — URINARY_TRACT

Explore this box plot interactively →