MFSD9

Across TCGA patient cohorts, MFSD9 mutation is significantly associated with the RNA expression of many other genes, with 1,023 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD9-associated genes across cancer lineages are HIKESHIP3, UBASH3B, and GPT2. Each is linked with MFSD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD9-to-partner and partner-to-MFSD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIKESHIP3 grouped by MFSD9-low versus MFSD9-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD9→partner) and Y-score (partner→MFSD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	HIKESHIP3 →	+0.161	+5.544	<.001	.004	3	2
UCEC	UBASH3B →	+0.714	+3.353	.001	.005	3	2
UCEC	GPT2 →	+0.760	+2.828	<.001	.001	3	2
UCEC	GOLGA3 →	+0.483	+2.828	<.001	.001	3	2
SKCM	RFC3P1 →	+0.029	+4.219	<.001	.006	3	2
COAD	RNA5SP297 →	+0.487	+2.992	.008	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,023 associations by consensus.

HIKESHIP3 by MFSD9 expression — LIHC

Explore this box plot interactively →