MFSD5

Across TCGA cell cohorts, MFSD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,904 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MFSD5-associated GO terms across cancer lineages are Lysosome organization, Lytic vacuole organization, and Vacuole organization. Each is linked with MFSD5 in more than 13 cancer types. Because this analysis shows association rather than direction, both MFSD5-to-partner and partner-to-MFSD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lysosome organization grouped by MFSD5-low versus MFSD5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD5→partner) and Y-score (partner→MFSD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.058	+0.474	<.001	.002	3	12
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.058	+0.474	<.001	.002	3	12
STOMACH	Vacuole organization →	+0.054	+0.383	.004	.007	1	14
SOFT_TISSUE	Process utilizing autophagic mechanism →	+0.041	+0.629	.006	.002	3	10
SOFT_TISSUE	Autophagy →	+0.041	+0.629	.006	.002	3	10
SKIN	Vacuolar transport →	+0.052	+0.506	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,904 associations by consensus.

Lysosome organization by MFSD5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →