Across TCGA patient cohorts, MFSD2B mutation is significantly associated with the RNA expression of many other genes, with 928 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD2B-associated genes across cancer lineages are TRAJ30, PSMA6P2, and MIR5583-1. Each is linked with MFSD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD2B-to-partner and partner-to-MFSD2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD2B→partner) and Y-score (partner→MFSD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ30 →	+1.079	+3.496	<.001	.002	3	2
COAD	PSMA6P2 →	+0.496	+3.354	.001	.008	3	2
COAD	MIR5583-1 →	+0.342	+4.332	<.001	.006	3	2
COAD	OR2Q1P →	+0.101	+4.136	<.001	.008	3	2
BLCA	ELMO2P1 →	+0.064	+4.429	.002	.006	3	2
LUAD	AQP7P3 →	+0.060	+5.410	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 928 associations by consensus.

Exploration

MFSD2B survival (RNA) · tumor vs normal (RNA) · all MFSD2B data types