MFSD2A

Across TCGA patient cohorts, MFSD2A mutation is significantly associated with the RNA expression of many other genes, with 840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD2A-associated genes across cancer lineages are RNU6-577P, LINC01241, and RNU7-13P. Each is linked with MFSD2A in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD2A-to-partner and partner-to-MFSD2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-577P grouped by MFSD2A-low versus MFSD2A-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD2A→partner) and Y-score (partner→MFSD2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU6-577P →	+0.786	+4.969	<.001	.009	3	2
LIHC	LINC01241 →	+0.049	+5.186	<.001	.007	3	2
GBM	RNU7-13P →	+0.674	+5.584	<.001	.003	3	2
BLCA	RNU6-271P →	+0.372	+7.307	<.001	<.001	3	2
UCEC	GSTM2 →	-0.707	-3.437	.002	.005	3	2
UCEC	MTND3P16 →	+0.051	+3.059	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 840 associations by consensus.

RNU6-577P by MFSD2A expression — GBM

Explore this box plot interactively →