MFSD14A

Across TCGA patient cohorts, MFSD14A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,167 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible MFSD14A-associated GO terms across cancer lineages are Protein sumoylation, 5S class rRNA transcription by RNA polymerase III, and RNA 3' uridylation. Each is linked with MFSD14A in more than 32 cancer types. Because this analysis shows association rather than direction, both MFSD14A-to-partner and partner-to-MFSD14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein sumoylation grouped by MFSD14A-low versus MFSD14A-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD14A→partner) and Y-score (partner→MFSD14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Protein sumoylation →	+0.065	+1.040	<.001	<.001	3	33
UCS	5S class rRNA transcription by RNA polymerase III →	+0.076	+0.872	<.001	<.001	3	33
DLBC	RNA 3' uridylation →	+0.099	+1.064	<.001	<.001	3	32
DLBC	Cellular response to ionizing radiation →	+0.076	+1.165	<.001	<.001	3	32
THYM	Golgi ribbon formation →	+0.093	+1.280	<.001	<.001	3	32
TGCT	Vesicle tethering involved in exocytosis →	+0.063	+0.835	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,167 associations by consensus.

Protein sumoylation by MFSD14A expression — DLBC

Explore this box plot interactively →