MFSD14A

Across TCGA cell cohorts, MFSD14A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,744 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD14A-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Positive regulation of cell cycle process, and Positive regulation of centriole replication. Each is linked with MFSD14A in more than 13 cancer types. Because this analysis shows association rather than direction, both MFSD14A-to-partner and partner-to-MFSD14A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by MFSD14A-low versus MFSD14A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD14A→partner) and Y-score (partner→MFSD14A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Zinc ion import into Golgi lumen →	+0.122	+1.172	<.001	<.001	3	14
BREAST	Positive regulation of cell cycle process →	+0.078	+0.731	.001	<.001	3	12
BLOOD_Myeloma	Positive regulation of centriole replication →	+0.121	+1.035	.004	<.001	3	12
OVARY	Pore complex assembly →	+0.114	+0.655	<.001	<.001	3	12
BONE	UDP-galactose transmembrane transport →	+0.151	+0.643	.001	.007	2	12
BLOOD_Myeloma	Regulation of centriole replication →	+0.080	+0.916	.003	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,744 associations by consensus.

Zinc ion import into Golgi lumen by MFSD14A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →