MFSD13B

Across TCGA pan-cancer cohorts, MFSD13B RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MFSD13B data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MFSD13B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MFSD13B expression acts as an unfavorable survival marker, although some lineages such as BLCA and THYM show a favorable association.

BLCA, THYM, and HNSC are the cancer types where MFSD13B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	II,III,IV	0.412	0.275	.001	64	view →
THYM	DFS	Tertile	All	1.000	0.550	.002	39	view →
HNSC	OS	Median	All	0.820	0.714	.003	37	view →
KIRC	DFS	Tertile	III,IV	0.342	0.577	.007	37	view →
BRCA	DFS	Tertile	III,IV	0.949	0.812	.003	33	view →
LGG	DFS	Tertile	All	0.780	0.893	<.001	26	view →
READ	DFS	Median	IV	0.389	0.814	.004	19	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	18	view →
COAD	DFS	Quartile	All	0.392	0.654	.016	16	view →
SKCM	OS	Tertile	III,IV	0.752	0.578	.017	14	view →
SARC	OS	Median	All	0.591	0.417	.006	14	view →
LUSC	DFS	Median	II,III,IV	0.614	0.839	.008	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MFSD13B–BLCA (DFS)

Open the BLCA breakdown →