MFSD13B

Across TCGA pan-cancer cohorts, MFSD13B RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MFSD13B’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MFSD13B RNA is repressed in tumor relative to normal tissue. In most cancer types MFSD13B is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, CHOL, and KIRC are the cancer types where MFSD13B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MFSD13B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.572	<.001	8	view →
CHOL	All	All	+1.197	<.001	3	view →
KIRC	All	All	+0.138	.010	2	view →
LIHC	Female	All	+0.094	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MFSD13B–THCA

Open the THCA breakdown →