MFSD13A

Across TCGA patient cohorts, MFSD13A mutation is significantly associated with the RNA expression of many other genes, with 1,448 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD13A-associated genes across cancer lineages are TIMM22, RDM1P2, and MRPL22P1. Each is linked with MFSD13A in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD13A-to-partner and partner-to-MFSD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM22 grouped by MFSD13A-low versus MFSD13A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD13A→partner) and Y-score (partner→MFSD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM22 →	+0.366	+3.053	.005	<.001	3	2
UCEC	RDM1P2 →	+0.049	+2.904	<.001	.009	3	2
COAD	MRPL22P1 →	+0.110	+2.740	<.001	.008	3	2
UCEC	RNY1P1 →	+0.182	+3.013	<.001	.007	3	2
UCEC	TDGF1P1 →	+0.081	+2.613	<.001	.006	3	2
UCEC	HMGB3P3 →	+0.167	+2.021	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,448 associations by consensus.

TIMM22 by MFSD13A expression — UCEC

Explore this box plot interactively →