MFSD13A

Across TCGA patient cohorts, MFSD13A mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD13A-associated genes across cancer lineages are GATA6, ACC1, and JNK_pT183_Y185. Each is linked with MFSD13A in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD13A-to-partner and partner-to-MFSD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATA6 grouped by MFSD13A-low versus MFSD13A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD13A→partner) and Y-score (partner→MFSD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA6 →	-0.225	-3.321	.003	.010	3	1
UCEC	ACC1 →	+0.334	+2.584	.048	.011	3	1
UCEC	JNK_pT183_Y185 →	-0.212	-2.571	.006	.011	3	1
UCEC	JNK2 →	+0.289	+2.179	.001	.034	3	1
UCEC	Ku80 →	+0.252	+1.887	.022	.031	3	1
UCEC	mTOR_pS2448 →	-0.166	-2.986	.016	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

GATA6 by MFSD13A expression — UCEC

Explore this box plot interactively →