MFSD13A

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MFSD13A mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD13A-associated genes across cancer lineages are C20orf85, IL22, and KRT71. Each is linked with MFSD13A in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD13A-to-partner and partner-to-MFSD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C20orf85 grouped by MFSD13A-low versus MFSD13A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD13A→partner) and Y-score (partner→MFSD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaC20orf85 →+0.029+4.384<.001.00631
BLOOD_LeukemiaIL22 →+0.030+4.984<.001.00231
BLOOD_LeukemiaKRT71 →+0.041+4.507<.001.00131
BLOOD_LeukemiaOR10R2 →+2.207+3.551<.001.00931
BLOOD_LeukemiaDMRTC1 →+0.194+3.855.005.00731
LARGE_INTESTINEFAM205A →+0.023+3.614<.001.00611
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C20orf85 by MFSD13A expression — BLOOD_Leukemia

Box plot of C20orf85 in MFSD13A-low vs MFSD13A-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration