MFSD13A

Across TCGA cell cohorts, MFSD13A mutation is significantly associated with the mutation status of many other genes, with 2,826 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD13A-associated genes across cancer lineages are VCPKMT, NAGLU, and PRG4. Each is linked with MFSD13A in more than 2 cancer types. Because this analysis shows association rather than direction, both MFSD13A-to-partner and partner-to-MFSD13A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VCPKMT grouped by MFSD13A-low versus MFSD13A-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD13A→partner) and Y-score (partner→MFSD13A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	VCPKMT →	+5.392	+5.392	.004	.004	1	3
UPPER_AERODIGESTIVE_TRACT	NAGLU →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	PRG4 →	+4.392	+4.954	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	SEC16B →	+5.392	+5.392	.004	.004	1	3
BLOOD_Leukemia	IMMT →	+5.247	+3.894	.001	.001	1	3
UPPER_AERODIGESTIVE_TRACT	CRIM1 →	+5.392	+5.392	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,826 associations by consensus.

VCPKMT by MFSD13A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →