MFSD12

Across TCGA cell cohorts, MFSD12 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFSD12-associated genes across cancer lineages are OR6J1, FOXN1, and GH2. Each is linked with MFSD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD12-to-partner and partner-to-MFSD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6J1 grouped by MFSD12-low versus MFSD12-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD12→partner) and Y-score (partner→MFSD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR6J1 →	+0.004	+4.643	<.001	.005	3	2
BLOOD_Leukemia	FOXN1 →	+0.026	+3.944	<.001	.006	3	1
BLOOD_Leukemia	GH2 →	+0.017	+4.384	<.001	.006	3	1
BLOOD_Leukemia	TEX47 →	+0.036	+4.269	.006	.002	3	1
BLOOD_Leukemia	GPR101 →	+0.116	+3.551	<.001	.009	3	1
BLOOD_Leukemia	OXGR1 →	+0.129	+3.847	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

OR6J1 by MFSD12 expression — BLOOD_Lymphoma

Explore this box plot interactively →