MFSD11

Across TCGA patient cohorts, MFSD11 protein abundance is significantly associated with the RNA expression of many other genes, with 4,204 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MFSD11-associated genes across cancer lineages are HSPG2, HLA-DQB1, and SERP2. Each is linked with MFSD11 in more than 2 cancer types. Because this analysis shows association rather than direction, both MFSD11-to-partner and partner-to-MFSD11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFSD11 versus HSPG2 in CCRCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD11→partner) and Y-score (partner→MFSD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HSPG2 →	-0.895	-0.357	<.001	.006	3	3
CCRCC	HLA-DQB1 →	+1.209	+0.491	<.001	<.001	3	3
PDAC	SERP2 →	-0.521	-0.470	<.001	.003	3	3
CCRCC	SPRY4 →	-0.909	-0.392	<.001	.007	3	3
CCRCC	LENG1 →	-0.431	-0.594	<.001	<.001	3	2
CCRCC	CDC42EP1 →	-0.856	-0.537	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,204 associations by consensus.

MFSD11 vs HSPG2 — CCRCC

Explore this scatter interactively →