MFSD11

Across TCGA patient cohorts, MFSD11 mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFSD11-associated genes across cancer lineages are MIR6737, NF1P10, and MIR425. Each is linked with MFSD11 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFSD11-to-partner and partner-to-MFSD11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6737 grouped by MFSD11-low versus MFSD11-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFSD11→partner) and Y-score (partner→MFSD11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6737 →	+0.381	+4.506	<.001	.001	3	2
CESC	NF1P10 →	+0.309	+5.569	<.001	<.001	3	2
UCEC	MIR425 →	+0.343	+2.399	.003	.001	3	2
UCEC	LINC02195 →	+0.701	+2.628	.002	.001	3	2
UCEC	RNA5SP413 →	+0.849	+2.107	.001	.003	3	2
CESC	OR2M4 →	+0.085	+4.837	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

MIR6737 by MFSD11 expression — BRCA

Explore this box plot interactively →