MFHAS1

Across TCGA pan-cancer cohorts, MFHAS1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MFHAS1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MFHAS1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MFHAS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, LUAD, and HNSC are the cancer types where MFHAS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.847	0.232	.023	4	view →
LUAD	OS	Median	All	1.000	0.773	.006	4	view →
HNSC	DFS	Quartile	IV	0.844	0.269	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MFHAS1–UCEC (DFS)

Open the UCEC breakdown →