MFHAS1

Across TCGA cell cohorts, MFHAS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,999 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MFHAS1-associated GO terms across cancer lineages are Negative regulation of toll-like receptor 2 signaling pathway, Negative regulation of heterochromatin organization, and Negative regulation of chromatin organization. Each is linked with MFHAS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both MFHAS1-to-partner and partner-to-MFHAS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of toll-like receptor 2 signaling pathway grouped by MFHAS1-low versus MFHAS1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFHAS1→partner) and Y-score (partner→MFHAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of toll-like receptor 2 signaling pathway →	+1.432	+2.012	<.001	<.001	3	14
LIVER	Negative regulation of heterochromatin organization →	+0.128	+1.458	.007	.003	3	13
URINARY_TRACT	Negative regulation of chromatin organization →	+0.120	+1.393	.001	<.001	3	13
LIVER	Negative regulation of heterochromatin formation →	+0.128	+1.458	.007	.003	3	13
LIVER	Regulation of heterochromatin formation →	+0.119	+1.582	.009	<.001	3	12
URINARY_TRACT	Regulation of regulatory ncRNA-mediated heterochromatin formation →	+0.142	+1.061	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,999 associations by consensus.

Negative regulation of toll-like receptor 2 signaling pathway by MFHAS1 expression — BONE

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