MFF

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MFF RNA expression is significantly associated with the protein abundance of many other proteins, with 10,523 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MFF-associated proteins across cancer lineages are MFF_S155, CUL3, and FARSB. Each is linked with MFF in more than 7 cancer types. Because this analysis shows association rather than direction, both MFF-to-partner and partner-to-MFF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFF versus MFF_S155 in PDAC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MFF→partner) and Y-score (partner→MFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACMFF_S155 →+0.534+0.183.001.00238
OVCUL3 →+0.318+0.455<.001<.00136
OVFARSB →+0.233+0.238.003.00535
OVNCL →+0.447+0.355<.001.00134
GBMORC3 →+0.298+0.470<.001<.00134
GBMSASH3 →-0.369-0.246.001.00834
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,523 associations by consensus.

MFF vs MFF_S155 — PDAC

Per-sample scatter of MFF vs MFF_S155 in PDAC (Pearson r = 0.41).

Explore this scatter interactively →

Exploration