MFF

Across TCGA patient cohorts, MFF protein abundance is significantly associated with the RNA expression of many other genes, with 8,626 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MFF-associated genes across cancer lineages are SIVA1, AJUBA, and PPP1R7. Each is linked with MFF in more than 4 cancer types. Because this analysis shows association rather than direction, both MFF-to-partner and partner-to-MFF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MFF versus SIVA1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFF→partner) and Y-score (partner→MFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SIVA1 →	-0.883	-0.335	<.001	<.001	3	5
UCEC	AJUBA →	-0.688	-0.219	.001	.006	3	4
LSCC	PPP1R7 →	+0.403	+0.317	<.001	<.001	3	3
LSCC	NDUFA10 →	+0.364	+0.268	<.001	<.001	3	3
LSCC	AGL →	+0.500	+0.287	<.001	<.001	3	3
CCRCC	TMEM92 →	+0.915	+0.233	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,626 associations by consensus.

MFF vs SIVA1 — UCEC

Explore this scatter interactively →