MFF

Across TCGA cell cohorts, MFF RNA expression is significantly associated with the go_rna of many other GO terms, with 2,506 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MFF-associated GO terms across cancer lineages are Regulation of DNA damage checkpoint, Epidermis development, and Epidermal cell differentiation. Each is linked with MFF in more than 8 cancer types. Because this analysis shows association rather than direction, both MFF-to-partner and partner-to-MFF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA damage checkpoint grouped by MFF-low versus MFF-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MFF→partner) and Y-score (partner→MFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of DNA damage checkpoint →	+0.062	+0.711	.002	<.001	2	9
BLOOD_Leukemia	Epidermis development →	-0.072	-0.395	.002	.001	3	8
LUNG_NSCLC_LUSC	Epidermal cell differentiation →	-0.116	-0.838	<.001	.006	2	8
UPPER_AERODIGESTIVE_TRACT	Multi-organism reproductive process →	-0.078	-0.562	.001	.004	3	7
BONE	Brainstem development →	+0.123	+0.430	<.001	<.001	3	7
SKIN	Phosphatidylglycerol metabolic process →	+0.053	+0.402	.009	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,506 associations by consensus.

Regulation of DNA damage checkpoint by MFF expression — BREAST

Explore this box plot interactively →