MFF-DT

Across TCGA pan-cancer cohorts, MFF-DT RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MFF-DT data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MFF-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MFF-DT expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.

UCS, UVM, and ACC are the cancer types where MFF-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	III,IV	0.598	0.225	.002	72	view →
UVM	DFS	Tertile	II,III,IV	0.296	0.733	.001	57	view →
ACC	DFS	Median	All	0.233	0.642	<.001	49	view →
LIHC	OS	Tertile	All	0.666	0.825	<.001	47	view →
UCEC	DFS	Tertile	All	0.799	0.902	<.001	42	view →
LUSC	OS	Median	II,III,IV	0.314	0.495	.008	33	view →
READ	OS	Median	II,III,IV	1.000	0.838	.004	30	view →
BRCA	OS	Quartile	All	0.383	0.644	<.001	23	view →
STAD	DFS	Quartile	II,III,IV	0.282	0.532	.014	22	view →
CESC	DFS	Tertile	All	0.794	0.902	.001	18	view →
HNSC	DFS	Quartile	II,III,IV	0.454	0.749	.008	10	view →
MESO	DFS	Quartile	III,IV	0.122	0.572	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MFF-DT–UCS (DFS)

Open the UCS breakdown →