MFAP4

Across TCGA patient cohorts, MFAP4 mutation is significantly associated with the RNA expression of many other genes, with 219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFAP4-associated genes across cancer lineages are RNU4-79P, RNU6-763P, and RER1. Each is linked with MFAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP4-to-partner and partner-to-MFAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-79P grouped by MFAP4-low versus MFAP4-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP4→partner) and Y-score (partner→MFAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU4-79P →	+0.213	+7.939	<.001	.008	3	2
PRAD	RNU6-763P →	+0.247	+7.939	<.001	.008	3	2
UCEC	RER1 →	+0.332	+3.491	.009	.002	3	1
UCEC	CLDND2 →	+0.568	+3.209	.006	.009	3	1
UCEC	NUDT2 →	+0.772	+3.202	<.001	.009	3	1
UCEC	MRPL58 →	+0.504	+3.201	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

RNU4-79P by MFAP4 expression — PRAD

Explore this box plot interactively →