MFAP4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MFAP4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFAP4-associated genes across cancer lineages are ATM and c-Kit. Each is linked with MFAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP4-to-partner and partner-to-MFAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MFAP4-low versus MFAP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP4→partner) and Y-score (partner→MFAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATM →-0.716-3.169.003.01931
UCECc-Kit →-0.262-3.169.041.02021
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ATM by MFAP4 expression — UCEC

Box plot of ATM in MFAP4-low vs MFAP4-high samples in UCEC.

Explore this box plot interactively →

Exploration