MFAP2

Across TCGA patient cohorts, MFAP2 mutation is significantly associated with the RNA expression of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MFAP2-associated genes across cancer lineages are RN7SL318P, OTP, and C2orf83. Each is linked with MFAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MFAP2-to-partner and partner-to-MFAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL318P grouped by MFAP2-low versus MFAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MFAP2→partner) and Y-score (partner→MFAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL318P →	+0.381	+2.860	<.001	.004	3	2
UCEC	OTP →	+0.102	+3.449	.009	.005	3	1
UCEC	C2orf83 →	+0.176	+3.225	<.001	.003	3	1
UCEC	DDX3Y →	+0.029	+2.581	.009	.009	3	1
SKCM	RNU6-1313P →	+0.313	+7.816	<.001	.008	3	1
UCEC	SNRPGP17 →	+0.332	+2.879	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

RN7SL318P by MFAP2 expression — UCEC

Explore this box plot interactively →