MEX3D

Across TCGA pan-cancer cohorts, MEX3D mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MEX3D’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MEX3D mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types MEX3D is over-expressed in tumor.

LUAD, LSCC, and HNSC are the cancer types where MEX3D tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MEX3D mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.413	<.001	5	view →
LSCC	All	All	+0.276	<.001	5	view →
HNSC	All	III,IV	+0.246	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MEX3D–LUAD

Open the LUAD breakdown →