MEX3D

Across TCGA cell cohorts, MEX3D RNA expression is significantly associated with the go_rna of many other GO terms, with 4,517 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEX3D-associated GO terms across cancer lineages are Mitotic chromosome condensation, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Regulation of protein localization to chromatin. Each is linked with MEX3D in more than 14 cancer types. Because this analysis shows association rather than direction, both MEX3D-to-partner and partner-to-MEX3D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic chromosome condensation grouped by MEX3D-low versus MEX3D-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEX3D→partner) and Y-score (partner→MEX3D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitotic chromosome condensation →	+0.115	+0.983	.005	<.001	3	15
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.122	+1.083	<.001	<.001	3	14
URINARY_TRACT	Regulation of protein localization to chromatin →	+0.153	+1.648	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of protein localization to chromatin →	+0.143	+1.136	.001	<.001	2	14
BONE	Negative regulation of DNA-templated transcription initiation →	+0.109	+1.143	<.001	<.001	3	13
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.109	+1.143	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,517 associations by consensus.

Mitotic chromosome condensation by MEX3D expression — BONE

Explore this box plot interactively →