MEX3B

Across TCGA patient cohorts, MEX3B mutation is significantly associated with the RNA expression of many other genes, with 3,178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEX3B-associated genes across cancer lineages are GEMIN4, CDCA2, and CNOT7. Each is linked with MEX3B in more than 2 cancer types. Because this analysis shows association rather than direction, both MEX3B-to-partner and partner-to-MEX3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GEMIN4 grouped by MEX3B-low versus MEX3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEX3B→partner) and Y-score (partner→MEX3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GEMIN4 →	+0.482	+2.828	<.001	.001	3	3
UCEC	CDCA2 →	+0.742	+3.828	<.001	<.001	3	3
UCEC	CNOT7 →	+0.490	+2.040	.001	.005	3	3
HNSC	ANKRD49P3 →	+0.059	+3.952	<.001	.005	3	3
UCEC	TUBB8P5 →	+0.340	+1.452	<.001	.007	3	3
UCEC	TYW3 →	+0.413	+2.458	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,178 associations by consensus.

GEMIN4 by MEX3B expression — UCEC

Explore this box plot interactively →