MEX3A

Across TCGA patient cohorts, MEX3A mutation is significantly associated with the RNA expression of many other genes, with 2,209 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEX3A-associated genes across cancer lineages are RN7SL763P, RN7SKP291, and RNA5SP93. Each is linked with MEX3A in more than 2 cancer types. Because this analysis shows association rather than direction, both MEX3A-to-partner and partner-to-MEX3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL763P grouped by MEX3A-low versus MEX3A-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEX3A→partner) and Y-score (partner→MEX3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RN7SL763P →	+0.099	+4.681	<.001	.006	3	3
ESCA	RN7SKP291 →	+0.185	+4.967	<.001	.002	3	3
COAD	RNA5SP93 →	+0.383	+4.087	<.001	.006	3	3
UCEC	CRYBB2P1 →	+0.470	+2.708	.003	.003	3	2
UCEC	HSCB →	+0.400	+2.032	.002	.005	3	2
UCEC	HMOX1 →	+0.690	+3.201	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,209 associations by consensus.

RN7SL763P by MEX3A expression — ESCA

Explore this box plot interactively →