METTL8P1

Across TCGA patient cohorts, METTL8P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,338 significant associations in total. STAD shows the largest number of these associations.

The most reproducible METTL8P1-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Mitochondrial RNA processing, and Obsolete mRNA methylation. Each is linked with METTL8P1 in more than 15 cancer types. Because this analysis shows association rather than direction, both METTL8P1-to-partner and partner-to-METTL8P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by METTL8P1-low versus METTL8P1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL8P1→partner) and Y-score (partner→METTL8P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Maturation of SSU-rRNA →	+0.066	+0.215	.005	.001	3	16
STAD	Mitochondrial RNA processing →	+0.042	+0.130	<.001	<.001	3	15
STAD	Obsolete mRNA methylation →	+0.039	+0.091	<.001	<.001	3	14
ESCA	Mitochondrial RNA modification →	+0.048	+0.184	.009	.005	1	16
UCS	Positive regulation of chromosome condensation →	+0.087	+0.271	<.001	.001	3	14
STAD	Mitochondrial tRNA processing →	+0.036	+0.125	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,338 associations by consensus.

Maturation of SSU-rRNA by METTL8P1 expression — ESCA

Explore this box plot interactively →