METTL21C

Across TCGA patient cohorts, METTL21C RNA expression is significantly associated with the protein abundance of many other proteins, with 10,603 significant associations in total. GBM shows the largest number of these associations.

The most reproducible METTL21C-associated proteins across cancer lineages are MAPK6_S189, CAST_S499, and AZU1. Each is linked with METTL21C in more than 3 cancer types. Because this analysis shows association rather than direction, both METTL21C-to-partner and partner-to-METTL21C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL21C versus MAPK6_S189 in LUAD, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL21C→partner) and Y-score (partner→METTL21C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MAPK6_S189 →	-0.578	-0.244	<.001	.001	3	4
GBM	CAST_S499 →	-0.734	-0.547	<.001	<.001	3	4
GBM	AZU1 →	-0.786	-0.403	.006	.004	3	3
HNSC	PGAM1_S31 →	-0.518	-0.469	<.001	<.001	3	3
HNSC	ZYX_S15 →	-0.687	-0.456	<.001	<.001	3	3
GBM	PHKA1_S758 →	-0.857	-0.505	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,603 associations by consensus.

METTL21C vs MAPK6_S189 — LUAD

Explore this scatter interactively →