METTL18

Across TCGA cell cohorts, METTL18 RNA expression is significantly associated with the RNA expression of many other genes, with 8,729 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible METTL18-associated genes across cancer lineages are TIPRL, C1orf112, and TADA1. Each is linked with METTL18 in more than 14 cancer types. Because this analysis shows association rather than direction, both METTL18-to-partner and partner-to-METTL18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL18 versus TIPRL in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.69.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL18→partner) and Y-score (partner→METTL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TIPRL →	+1.057	+0.984	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	C1orf112 →	+1.631	+1.030	<.001	<.001	3	14
BONE	TADA1 →	+0.747	+0.632	<.001	<.001	3	13
OESOPHAGUS	GGPS1 →	+1.057	+0.824	.001	<.001	3	13
BLOOD_Myeloma	BLZF1 →	+1.162	+0.708	.001	.004	1	15
UPPER_AERODIGESTIVE_TRACT	GORAB →	+1.216	+0.778	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,729 associations by consensus.

METTL18 vs TIPRL — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →