METTL17

Across TCGA patient cohorts, METTL17 protein abundance is significantly associated with the RNA expression of many other genes, with 11,167 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible METTL17-associated genes across cancer lineages are CKS2, DLGAP5, and CDC25C. Each is linked with METTL17 in more than 4 cancer types. Because this analysis shows association rather than direction, both METTL17-to-partner and partner-to-METTL17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL17 versus CKS2 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL17→partner) and Y-score (partner→METTL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CKS2 →	+1.155	+0.437	.006	<.001	3	5
HNSC	DLGAP5 →	+0.970	+0.358	.003	.002	3	5
UCEC	CDC25C →	+0.748	+0.220	.006	.005	3	5
LSCC	IL16 →	-0.593	-0.315	.003	.008	3	5
LSCC	SH3BGRL →	-0.868	-0.480	<.001	<.001	3	4
BRCA	NECAP2 →	-0.393	-0.264	.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,167 associations by consensus.

METTL17 vs CKS2 — HNSC

Explore this scatter interactively →