METTL16

Across TCGA patient cohorts, METTL16 protein abundance is significantly associated with the RNA expression of many other genes, with 11,088 significant associations in total. GBM shows the largest number of these associations.

The most reproducible METTL16-associated genes across cancer lineages are SRR, RPAIN, and PRPSAP2. Each is linked with METTL16 in more than 7 cancer types. Because this analysis shows association rather than direction, both METTL16-to-partner and partner-to-METTL16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL16 versus SRR in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL16→partner) and Y-score (partner→METTL16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SRR →	+0.430	+0.299	.002	<.001	3	8
LSCC	RPAIN →	+0.567	+0.256	<.001	<.001	3	7
LSCC	PRPSAP2 →	+0.648	+0.257	<.001	<.001	3	7
OV	CNTROB →	+0.653	+0.387	<.001	<.001	3	7
OV	GEMIN4 →	+0.824	+0.382	<.001	<.001	3	7
LSCC	PIGL →	+0.528	+0.271	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,088 associations by consensus.

METTL16 vs SRR — OV

Explore this scatter interactively →