METTL15

Across TCGA patient cohorts, METTL15 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,266 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible METTL15-associated proteins across cancer lineages are TSG101, C11orf58, and DBI_Y29. Each is linked with METTL15 in more than 4 cancer types. Because this analysis shows association rather than direction, both METTL15-to-partner and partner-to-METTL15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, METTL15 versus TSG101 in PDAC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (METTL15→partner) and Y-score (partner→METTL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TSG101 →	+0.247	+0.298	.001	.001	3	5
BRCA	C11orf58 →	+0.335	+0.498	<.001	<.001	3	5
BRCA	DBI_Y29 →	-0.528	-0.385	<.001	.002	3	4
BRCA	FNBP1 →	-0.308	-0.386	<.001	.002	3	4
BRCA	UBE2J1 →	-0.615	-0.537	<.001	<.001	3	4
LSCC	VEZF1 →	+0.381	+0.446	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,266 associations by consensus.

METTL15 vs TSG101 — PDAC

Explore this scatter interactively →