MESP1

Across TCGA cell cohorts, MESP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,840 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MESP1-associated GO terms across cancer lineages are Somite rostral/caudal axis specification, Regulation of endodermal cell differentiation, and Cardiac vascular smooth muscle cell differentiation. Each is linked with MESP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both MESP1-to-partner and partner-to-MESP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somite rostral/caudal axis specification grouped by MESP1-low versus MESP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MESP1→partner) and Y-score (partner→MESP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Somite rostral/caudal axis specification →	+1.101	+1.992	<.001	<.001	3	12
BONE	Regulation of endodermal cell differentiation →	-0.307	-1.113	<.001	<.001	3	11
BLOOD_Myeloma	Cardiac vascular smooth muscle cell differentiation →	-0.284	-1.150	.002	.001	2	12
BREAST	Cardiac cell fate determination →	+0.765	+1.869	<.001	<.001	3	10
BLOOD_Leukemia	Proton motive force-driven ATP synthesis →	+0.077	+0.635	<.001	<.001	3	8
BLOOD_Myeloma	Cell migration involved in heart development →	-0.244	-1.074	.004	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,840 associations by consensus.

Somite rostral/caudal axis specification by MESP1 expression — BREAST

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