MEP1B

Across TCGA patient cohorts, MEP1B protein abundance is significantly associated with the RNA expression of many other genes, with 706 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MEP1B-associated genes across cancer lineages are SH3BP1, SPEF1, and PPP1R16B. Each is linked with MEP1B in more than 1 cancer types. Because this analysis shows association rather than direction, both MEP1B-to-partner and partner-to-MEP1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEP1B versus SH3BP1 in PDAC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEP1B→partner) and Y-score (partner→MEP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SH3BP1 →	-0.782	-0.915	.003	<.001	3	1
PDAC	SPEF1 →	-0.425	-0.996	<.001	.001	3	1
PDAC	PPP1R16B →	-0.626	-0.625	<.001	.004	3	1
PDAC	ALG13 →	-0.407	-0.632	.003	.004	3	1
PDAC	ZNF629 →	-0.426	-0.914	.004	.002	3	1
PDAC	GIPR →	-0.802	-0.903	.005	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 706 associations by consensus.

MEP1B vs SH3BP1 — PDAC

Explore this scatter interactively →