MEP1B

Across TCGA patient cohorts, MEP1B mutation is significantly associated with the RNA expression of many other genes, with 5,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEP1B-associated genes across cancer lineages are SLC25A22, RPS27P20, and EIF4EBP3. Each is linked with MEP1B in more than 2 cancer types. Because this analysis shows association rather than direction, both MEP1B-to-partner and partner-to-MEP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A22 grouped by MEP1B-low versus MEP1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEP1B→partner) and Y-score (partner→MEP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC25A22 →	+0.358	+1.745	.001	.004	3	3
COAD	RPS27P20 →	+0.347	+3.496	<.001	.008	3	2
SKCM	EIF4EBP3 →	-0.741	-3.584	.002	.002	3	2
READ	MIR4774 →	+0.627	+5.257	<.001	.002	3	2
UCEC	LAMTOR1 →	+0.371	+1.818	<.001	<.001	3	2
UCEC	HYOU1 →	+0.617	+2.662	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,174 associations by consensus.

SLC25A22 by MEP1B expression — UCEC

Explore this box plot interactively →