MEP1B

Across TCGA cell cohorts, MEP1B mutation is significantly associated with the drug of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEP1B-associated genes across cancer lineages are Bromosporine, Fulvestrant, and JNJ38877605. Each is linked with MEP1B in more than 1 cancer types. Because this analysis shows association rather than direction, both MEP1B-to-partner and partner-to-MEP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Bromosporine grouped by MEP1B-low versus MEP1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEP1B→partner) and Y-score (partner→MEP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Bromosporine →	+0.352	+2.649	.041	.046	3	1
LARGE_INTESTINE	Fulvestrant →	+0.502	+2.684	.002	.035	3	1
LARGE_INTESTINE	JNJ38877605 →	+0.416	+2.786	.015	.037	3	1
LARGE_INTESTINE	Masitinib →	+0.430	+2.652	.046	.045	3	1
LARGE_INTESTINE	BIBF-1120 →	+0.574	+2.652	.012	.045	3	1
LARGE_INTESTINE	kb NB 142-70 →	+0.576	+2.652	.013	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Bromosporine by MEP1B expression — LARGE_INTESTINE

Explore this box plot interactively →