Across TCGA pan-cancer cohorts, MEP1AP4 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MEP1AP4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MEP1AP4 RNA is repressed in tumor relative to normal tissue. In most cancer types MEP1AP4 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, READ, and UCEC are the cancer types where MEP1AP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MEP1AP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−1.689	<.001	7	view →
READ	All	All	−1.006	.008	3	view →
UCEC	All	IV	+0.135	.032	2	view →
LIHC	All	All	+0.019	.030	1	view →
KIRP	All	All	+0.008	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: MEP1AP4 RNA expression & survival · all MEP1AP4 data types