meprin A subunit alpha pseudogene 4Genealiases: []
Q-omics provides the consensus-scored MEP1AP4 profile across patient tissues and cancer cell-line models. MEP1AP4 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, MEP1AP4 is differentially expressed in 5, with the highest sampling consensus in COAD. Additionally, MEP1AP4 RNA expression shows 6,450 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight THCA, COAD, and ESCA as cancer lineages where MEP1AP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MEP1AP4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MEP1AP4 survival associations across molecular data types. MEP1AP4 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MEP1AP4 RNA expression–survival associations across cancer types. High MEP1AP4 expression shows unfavorable associations in THCA, THYM, COAD, LIHC, ESCA and SARC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for MEP1AP4 RNA expression.
This table summarizes MEP1AP4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MEP1AP4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MEP1AP4 shows lower tumor expression in COAD and READ and higher tumor expression in UCEC, LIHC and KIRP. The COAD box plot shows higher MEP1AP4 RNA expression in normal versus tumor tissue (log2 FC = −1.689, t-test p < 0.001).
This table shows molecular features associated with MEP1AP4 in patient tissues and cancer cell lines. In patient samples, MEP1AP4 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
