MEOX2

Across TCGA cell cohorts, MEOX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 727 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MEOX2-associated GO terms across cancer lineages are Endocytic recycling, Proton motive force-driven mitochondrial ATP synthesis, and SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Each is linked with MEOX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MEOX2-to-partner and partner-to-MEOX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endocytic recycling grouped by MEOX2-low versus MEOX2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEOX2→partner) and Y-score (partner→MEOX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Endocytic recycling →	+0.049	+0.047	<.001	.005	3	3
BLOOD_Lymphoma	Proton motive force-driven mitochondrial ATP synthesis →	+0.072	+0.051	<.001	.007	3	3
LUNG_SCLC	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.089	+2.389	<.001	<.001	3	3
LARGE_INTESTINE	Regulation of mRNA splicing, via spliceosome →	+0.047	+0.029	.001	.002	2	4
BREAST	Positive regulation of low-density lipoprotein particle clearance →	+0.068	+0.038	.006	.007	2	4
CNS	Long-chain fatty acid transport →	-0.044	-1.271	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 727 associations by consensus.

Endocytic recycling by MEOX2 expression — BLOOD_Lymphoma

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