MEN1

Across TCGA patient cohorts, MEN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,626 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MEN1-associated proteins across cancer lineages are SF3B3, CPSF7, and FEN1. Each is linked with MEN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MEN1-to-partner and partner-to-MEN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEN1 versus SF3B3 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEN1→partner) and Y-score (partner→MEN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.235	+0.296	.002	.008	3	7
GBM	CPSF7 →	+0.378	+0.422	<.001	<.001	3	7
HNSC	FEN1 →	+0.485	+0.649	<.001	<.001	3	7
LSCC	SUPT16H →	+0.423	+0.431	<.001	<.001	3	6
GBM	ZMYM3 →	+0.376	+0.396	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.350	+0.451	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,626 associations by consensus.

MEN1 vs SF3B3 — GBM

Explore this scatter interactively →