MELTF

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MELTF protein abundance is significantly associated with the RNA expression of many other genes, with 1,983 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MELTF-associated genes across cancer lineages are TJP3, ZSCAN22, and ZNF324B. Each is linked with MELTF in more than 1 cancer types. Because this analysis shows association rather than direction, both MELTF-to-partner and partner-to-MELTF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MELTF versus TJP3 in BLOOD_Lymphoma, with a Pearson correlation of -0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MELTF→partner) and Y-score (partner→MELTF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTJP3 →-1.832-1.749<.001<.00132
BLOOD_LymphomaZSCAN22 →-0.617-1.700.005.00432
BLOOD_LymphomaZNF324B →-0.997-1.852.009.00332
BLOOD_LymphomaORAI1 →-1.759-1.612.006.00432
BLOOD_LymphomaZNF324 →-1.427-2.002.003<.00132
BREASTHBD →-0.105-1.871.008.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,983 associations by consensus.

MELTF vs TJP3 — BLOOD_Lymphoma

Per-sample scatter of MELTF vs TJP3 in BLOOD_Lymphoma (Pearson r = -0.82).

Explore this scatter interactively →

Exploration